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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ifngr1tm1Agt
Name: interferon gamma receptor 1; targeted mutation 1, Michel Aguet
MGI ID: MGI:1857286
Synonyms: G129, IFN-gamma R-, IFN-gammaR-, IFN-gammaR-, IFN-gamma R0, IFN-gammaR0, IFN-gammaR1-, IFN-gammaRalpha_, IFN-gamma-R KO, IFN-gammaR KO, IFNgammaR KO, Ifngr-, Ifngr1-, IFNgR KO, IFn type II receptor
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Trpm2tm1.1Alp/Trpm2tm1.1Alp and Ifngr1tm1Agt/Ifngr1tm1Agt mice exhibit increased susceptibility to bacterial infectionIfngr1tm1Agt/Ifngr1tm1Agtinvolves: 129S7/SvEvBrd
Trpm2tm1.1Alp/Trpm2tm1.1AlpB6.129P2-Trpm2tm1.1Alp
Increased osteolytic lesion formation and enhanced osteoclast activity in Ifngr1tm1Agt/Ifngr1tm1Agt Tg(GZMB-Tax)#Lera/0 miceIfngr1tm1Agt/Ifngr1tm1Agt
Tg(GZMB-Tax)#Lera/0
involves: 129S7/SvEvBrd * C57BL/6
Enhanced osteoclast formation in Ifngr1tm1Agt/Ifngr1tm1Agt Tg(GZMB-Tax)#Lera/0 miceIfngr1tm1Agt/Ifngr1tm1Agt
Tg(GZMB-Tax)#Lera/0
involves: 129S7/SvEvBrd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory