Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Xpa^tm1Hvs
Name:	xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg
MGI ID:	MGI:1857939
Synonyms:	XPA-, XpaKO

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Microglia activation in the white matter in Ercc2, Ercc6, and Ercc8 mutants	Ercc8^tm1Jhjh/Ercc8^tm1Jhjh	involves: 129P2/OlaHsd * C57BL/6J
		Ercc6^tm1Gvh/Ercc6^tm1Gvh	involves: 129P2/OlaHsd * C57BL/6J
		Ercc2^tm3Jhjh/Ercc2^tm3Jhjh	involves: 129 * C57BL/6J
	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(CAG-cre)13Miya/0 mice are severely reduced in size	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(CAG-cre)13Miya/0	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
	Dilated ventricles and brain atrophy in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 mice	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0	involves: 129P2/OlaHsd * C57BL/6J * CBA
	Neurodegenerative changes in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 brains	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0	involves: 129P2/OlaHsd * C57BL/6J * CBA
	Neurodegenerative changes in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Pcp2-cre)2Mpin/0 mice	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Pcp2-cre)2Mpin/0	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
	Weight loss in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 mice	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0	involves: 129P2/OlaHsd * C57BL/6J * CBA
	Brain atrophy after forebrain neuron-specific knockout of Xpa in Ercc6^tm1Gvh/Ercc6^tm1Gvh mice	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0	involves: 129P2/OlaHsd * C57BL/6J * CBA
	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mice display postnatal growth retardation	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs	involves: 129P2/OlaHsd * C57BL/6J
	Skeletal and neurological abnormalities in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mice	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs	B6.129P2-Xpa^tm1Hvs Ercc6^tm1Gvh
	Enhanced sensitivity of Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs retinal photoreceptor cells to ionizing radiation	Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs	B6.129P2-Xpa^tm1Hvs Ercc6^tm1Gvh

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