About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Itgb1tm1Ref
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Reinhard Fassler
MGI ID: MGI:1926498
Synonyms: beta1fl, beta1 integrin (fl), floxed beta1 integrin
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hair and skin phenotypes of various keratinocyte conditional Itgb1 allelesItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm12.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Defective adhesion and spreading of Itgb1tm1Ref/Itgb1tm12.1Ref Tg(KRT5-cre)5132Jlj/0 primary keratinocytesItgb1tm1Ref/Itgb1tm12.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Progressive hair loss in Itgb1tm1Ref/Itgb1tm5.1Ref Tg(KRT5-cre)5132Jlj/0 and Itgb1tm1Ref/Itgb1tm1Ref Tg(KRT5-cre)5132Jlj/0 miceItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Epidermal and hair follicle abnormalities in Itgb1tm1Ref/Itgb1tm5.1Ref Tg(KRT5-cre)5132Jlj/0 and Itgb1tm1Ref/Itgb1tm1Ref Tg(KRT5-cre)5132Jlj/0 miceItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm5.1Ref Tg(KRT5-cre)5132Jlj/0 keratinocytes show reduced spreadingItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory