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Phenotype Images associated with this Allele
Nomenclature
Symbol: Itgb1tm1Efu
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Elaine Fuchs
MGI ID: MGI:1926499
Synonyms: beta1e3, beta1flox, CD29f, integrin beta1flox, Itgb1f, Itgb1flox
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
The distal small and proximal large intestines of Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 mice have a larger diameterItgb1tm1Efu/Itgb1tm1Efu
Tg(Vil1-cre)997Gum/0
involves: 129X1/SvJ * C57BL/6J * SJL
Crypt hyperplasia and dysplasia and villous enlargement in Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 miceItgb1tm1Efu/Itgb1tm1Efu
Tg(Vil1-cre)997Gum/0
involves: 129X1/SvJ * C57BL/6J * SJL
Small intestinal polyps, lipid inclusions, and defective microvilli in Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 miceItgb1tm1Efu/Itgb1tm1Efu
Tg(Vil1-cre)997Gum/0
involves: 129X1/SvJ * C57BL/6J * SJL
Intestinal hyperproliferation in the Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 miceItgb1tm1Efu/Itgb1tm1Efu
Tg(Vil1-cre)997Gum/0
involves: 129X1/SvJ * C57BL/6J * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory