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Phenotype Images associated with this Allele
Nomenclature
Symbol: Cdkn2atm1Cjs
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
MGI ID: MGI:1926877
Synonyms: ARF-, p19Arf-, p19ARF-, p19Arf-null
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Metastasis of primary squamous cell carcinoma to lymph nodes and lungs in Cdkn2atm1Cjs/Cdkn2atm1Cjs miceCdkn2atm1Cjs/Cdkn2atm1Cjsinvolves: 129X1/SvJ * C57BL/6 * NIH/OlaHsd
Tumor multiplicity and proliferation index in Cdkn2atm1Cjs/Cdkn2atm1Cjs, Trp53tm1Brd/Trp53tm1Brd and Cdkn2atm1Cjs/Cdkn2atm1Cjs Trp53tm1Brd/Trp53tm1Brd miceCdkn2atm1Cjs/Cdkn2atm1Cjsinvolves: 129X1/SvJ * C57BL/6 * NIH/OlaHsd
Trp53tm1Brd/Trp53tm1BrdNIHOla.129S7-Trp53tm1Brd
Cdkn2atm1Cjs/Cdkn2atm1Cjs
Trp53tm1Brd/Trp53tm1Brd		involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * NIH/OlaHsd
Abnormal retrolental tissue present in the eyes of neonatal Cdkn2atm1Cjs/Cdkn2atm1Cjs miceCdkn2atm1Cjs/Cdkn2atm1Cjsinvolves: 129X1/SvJ * C57BL/6
Retrolental tissue in Cdkn2atm1Cjs/Cdkn2atm1Cjs mice contains mature hyaloid vascular structures and endothelial cellsCdkn2atm1Cjs/Cdkn2atm1Cjsinvolves: 129X1/SvJ * C57BL/6
PHPV-like abnormalities develop in Cdkn2atm1Cjs/Cdkn2atm1Cjs mouse eyesCdkn2atm1Cjs/Cdkn2atm1Cjsinvolves: 129X1/SvJ * C57BL/6
Persistent hyperplastic primary vitreous (PHPV) in Cdkn2atm1Cjs/Cdkn2atm1Cjs mice is p53 independentCdkn2atm1Cjs/Cdkn2atm1Cjsinvolves: 129X1/SvJ * C57BL/6
Cdkn2atm1Cjs/Cdkn2atm1Cjs
Trp53tm1Tyj/Trp53tm1Tyj		involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory