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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ctsltm1Cptr
Name: cathepsin L; targeted mutation 1, Christoph Peters
MGI ID: MGI:2136432
Synonyms: catL-, Cat L-, CL-, ctsl-, L-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Epidermal hyperplasia inCtsltm1Cptr/Ctsltm1Cptr and Ctsltm1.2Thre/Ctsltm1.2Thre miceCtsltm1.2Thre/Ctsltm1.2Threinvolves: C57BL/6 * C57BL/6N
Ctsltm1Cptr/Ctsltm1Cptrinvolves: 129P2/OlaHsd
Ctsltm1Cptr/Ctsltm1Cptr embryos show severe accumulation of vesicles in the yolk sac endodermCtsltm1Cptr/Ctsltm1Cptrinvolves: 129P2/OlaHsd
Cerebral and cerebellar atrophy in Ctsbtm1Jde/Ctsbtm1Jde Ctsltm1Cptr/Ctsltm1Cptr miceCtsbtm1Jde/Ctsbtm1Jde
Ctsltm1Cptr/Ctsltm1Cptr
involves: 129P2/OlaHsd * C57BL/6J
Apoptotic cell and neuron death in Ctsbtm1Jde/Ctsbtm1Jde Ctsltm1Cptr/Ctsltm1Cptr miceCtsbtm1Jde/Ctsbtm1Jde
Ctsltm1Cptr/Ctsltm1Cptr
involves: 129P2/OlaHsd * C57BL/6J
Accumulation of amorphous and membranous material in neuronal perikarya, dendrites, and axons in Ctsbtm1Jde/Ctsbtm1Jde Ctsltm1Cptr/Ctsltm1Cptr miceCtsbtm1Jde/Ctsbtm1Jde
Ctsltm1Cptr/Ctsltm1Cptr
involves: 129P2/OlaHsd * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory