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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Pcp2-cre)2Mpin
Name: transgene insertion 2, Max-Planck-Institute of Neurobiology
MGI ID: MGI:2137515
Synonyms: L7-cre, L7Cre-2, pcp2Cre-2
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Purkinje cell degeneration in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 miceAfg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Abnormal mitochondria in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 Purkinje cellsAfg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Abnormal mitochondrial network in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+ miceAfg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Few Purkinje cells survive in 12 week old Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 miceAfg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Evolution of mitochondrial morphology in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+ miceAfg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Neurodegeneration in Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Nes-cre)1Kln/0 and Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Pcp2-cre)2Mpin/0 brainsVps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Nes-cre)1Kln/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL
Vps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Pcp2-cre)2Mpin/0		B.129-Vps18tm1.1Wtao Tg(Pcp2-cre)2Mpin
Neurodegenerative changes in Ercc6tm1Gvh/Ercc6tm1Gvh Xpatm1Gvh/Xpatm1Hvs Tg(Pcp2-cre)2Mpin/0 miceErcc6tm1Gvh/Ercc6tm1Gvh
Xpatm1Gvh/Xpatm1Hvs
Tg(Pcp2-cre)2Mpin/0		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory