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Phenotype Images associated with this Allele
Nomenclature
Symbol: Rxratm4Ipc
Name: retinoid X receptor alpha; targeted mutation 4, Pierre Chambon
MGI ID: MGI:2153828
Synonyms: RxralphaL2
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 mice develop a chronic skin inflammationRxratm4Ipc/Rxratm4Ipc
Rxrbtm1Pcn/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0
involves: 129S2/SvPas
Characterization of inflammatory cell infiltrates in ear skin of Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 miceRxratm4Ipc/Rxratm4Ipc
Rxrbtm1Pcn/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0
involves: 129S2/SvPas
Systemic immunological abnormalities in Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 miceRxratm4Ipc/Rxratm4Ipc
Rxrbtm1Pcn/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0
involves: 129S2/SvPas
Rxratm1Ipc/Rxratm4Ipc Rxrbtm1Mma/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 mice develop alopecia but no skin inflammation while Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 mice show both hair loss and skin inflammationRxratm4Ipc/Rxratm4Ipc
Rxrbtm1Pcn/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0
involves: 129S2/SvPas
Rxratm1Ipc/Rxratm4Ipc
Rxrbtm1Mma/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0
involves: 129S2/SvPas

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory