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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dsc1tm1Dga
Name: desmocollin 1; targeted mutation 1, David R Garrod
MGI ID: MGI:2156926
Synonyms: Dsc1-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Eye, skin and growth abnormailities in Dsc1tm1Dga/Dsc1tm1Dga miceDsc1tm1Dga/Dsc1tm1Dgainvolves: C57BL/6J
Hyperplasia and increased cell proliferation in Dsc1tm1Dga/Dsc1tm1Dga epidermisDsc1tm1Dga/Dsc1tm1Dgainvolves: C57BL/6J
Dsc1tm1Dga/Dsc1tm1Dga mice exhibit weakened adhesion in the upper epidermis despite ultrastructurally normal desmosomesDsc1tm1Dga/Dsc1tm1Dgainvolves: C57BL/6J
Dsc1tm1Dga/Dsc1tm1Dga mice have skin barrier defectsDsc1tm1Dga/Dsc1tm1Dgainvolves: C57BL/6J
The abnormal skin, coat and growth phenotype of Dsc1tm1Dga/Dsc1tm1Dga mice increases in severity with ageDsc1tm1Dga/Dsc1tm1Dgainvolves: C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory