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Phenotype Images associated with this Allele
Nomenclature
Symbol: Bmpr1atm2.1Bhr
Name: bone morphogenetic protein receptor, type 1A; targeted mutation 2.1, Richard R Behringer
MGI ID: MGI:2158390
Synonyms: ALK3F, Alk3flox, Bmpr1af, Bmpr1a fl, Bmpr1afl, Bmpr1a fx, Bmpr1afx, Bmpr1afx(exon2), Bmpr1atm1.1Cren, BmpRIAflox, floxP
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Joint defects in Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr Tg(Gdf5-cre,-ALPP)1Kng/0 miceBmpr1atm2.1Bhr/Bmpr1atm2.2Bhr
Tg(Gdf5-cre,-ALPP)1Kng/0		involves: 129 * C57BL/6 * FVB/N-Tg(Gdf5-cre-ALPP)1Kng
Lack of tissue regression in Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr Tg(Gdf5-cre,-ALPP)1Kng/0 miceBmpr1atm2.1Bhr/Bmpr1atm2.2Bhr
Tg(Gdf5-cre,-ALPP)1Kng/0		involves: 129 * C57BL/6 * FVB/N-Tg(Gdf5-cre-ALPP)1Kng
Skeletal abnormalities in Bmpr1btm1Kml/Bmpr1btm1Kml, Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Tg(Col2a1-cre)1Bhr/?, and Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1btm1Kml/Bmpr1btm1Kmlinvolves: 129S/SvEv
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Tg(Col2a1-cre)1Bhr/?		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Impaired chondrocyte differentiation in Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Impaired chondrogenesis and extracellular matrix expression in Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Reduced rates of proliferation and cell survival in cartilage elements of Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? embryosBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory