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Phenotype Images associated with this Allele
Nomenclature
Symbol: Engtm1Mle
Name: endoglin; targeted mutation 1, Michelle Letarte
MGI ID: MGI:2177824
Synonyms: End -, Eng-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Arrest in development in Engtm1Mle/Engtm1Mle embryosEngtm1Mle/Engtm1Mleinvolves: 129P2/OlaHsd * C57BL/6
Vascular defects in Engtm1Mle/Engtm1Mle miceEngtm1Mle/Engtm1Mleinvolves: 129P2/OlaHsd * C57BL/6
Heart deficiency in Engtm1Mle/Engtm1Mle miceEngtm1Mle/Engtm1Mleinvolves: 129P2/OlaHsd * C57BL/6
Engtm1Mle/Eng+ mice have nosebleeds and telangiectases characteristic of heriditary hemorrhagic telangiectasiaEngtm1Mle/Eng+129P2/OlaHsd-Engtm1Mle
Microscopic examination of a telangiectasia from a Engtm1Mle/Eng+ mouseEngtm1Mle/Eng+129P2/OlaHsd-Engtm1Mle
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory