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Phenotype Images associated with this Allele
Nomenclature
Symbol: Tbx1tm1Bld
Name: T-box 1; targeted mutation 1, Antonio Baldini
MGI ID: MGI:2179136
Synonyms: Tbx1-, Tbx1lacZ
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Failure of inner ear morphogenesis in Tbx1tm1Bld/Tbx1tm1Bld mice at E14.5 and partial rescue of inner ear morphogenesis in Tbx1tm6(cre)Bld/Tbx1tm1Bld Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/ Gt(ROSA)26Sor+ miceTbx1tm1Bld/Tbx1tm1Bldinvolves: 129S7/SvEvBrd
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+
Tbx1tm1Bld/Tbx1tm6(cre)Bld		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem can patially rescue heart phenotypes in Tbx1tm6(cre)Bld/Tbx1tm1Bld miceGt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+
Tbx1tm1Bld/Tbx1tm6(cre)Bld		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem
Tbx1tm1Bld/Tbx1tm6(cre)Bld		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Pharyngeal arch artery patterning defects in Chd7Whi/Chd7+, Chd7Gt(XK403)Byg/Chd7+ and Chd7Gt(XK403)Byg/Chd7+ Tbx1tm1Bld/Tbx1+ embryosChd7Gt(XK403)Byg/Chd7+involves: 129P2/OlaHsd * C57BL/6
Chd7Gt(XK403)Byg/Chd7+
Tbx1tm1Bld/Tbx1+		either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)
Chd7Whi/Chd7+B6.C3Fe-Chd7Whi
Malformations of the semicircular canals in Chd7Whi/Chd7+, Tbx1tm1Bld/Tbx1+, and Chd7Whi/Chd7+ Tbx1tm1Bld/Tbx1+ miceTbx1tm1Bld/Tbx1+B6.129S7-Tbx1tm1Bld
Chd7Whi/Chd7+B6.C3Fe-Chd7Whi
Chd7Whi/Chd7+
Tbx1tm1Bld/Tbx1+		B6.Cg-Chd7Whi Tbx1tm1Bld
Cleft palate, absent thymus and ear and cardiovascular abnormalities in Tbx1tm1Bld/Tbx1tm1Bld miceTbx1tm1Bld/Tbx1tm1Bldinvolves: 129S7/SvEvBrd
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory