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Phenotype Images associated with this Allele
Nomenclature
Symbol: Nefmtm1Ral
Name: neurofilament, medium polypeptide; targeted mutation 1, Robert A Lazzarini
MGI ID: MGI:2180135
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lumbar root axon abnormalities in Nefmtm1Ral/Nefmtm1Ral and Nefhtm1Ral/Nefhtm1Ral Nefmtm1Ral/Nefmtm1Ral mice, but not Nefhtm1Ral/Nefhtm1Ral miceNefmtm1Ral/Nefmtm1Ralinvolves: 129S1/Sv * 129X1/SvJ
Nefhtm1Ral/Nefhtm1Ralinvolves: 129S1/Sv * 129X1/SvJ
Nefhtm1Ral/Nefhtm1Ral
Nefmtm1Ral/Nefmtm1Ral		involves: 129S1/Sv * 129X1/SvJ
Depletion of neurofilaments in ventral root axons of Nefmtm1Ral/Nefmtm1Ral and Nefmtm1Ral/Nefmtm1Ral Nefhtm1Ral/Nefhtm1Ral mice but not in Nefhtm1Ral/Nefhtm1Ral miceNefmtm1Ral/Nefmtm1Ralinvolves: 129S1/Sv * 129X1/SvJ
Nefhtm1Ral/Nefhtm1Ralinvolves: 129S1/Sv * 129X1/SvJ
Nefhtm1Ral/Nefhtm1Ral
Nefmtm1Ral/Nefmtm1Ral		involves: 129S1/Sv * 129X1/SvJ
Ventral root axons of Nefmtm1Ral/Nefmtm1Ral and Nefmtm1Ral/Nefmtm1Ral Nefhtm1Ral/Nefhtm1Ral mice become shrunken and irregular in shape with ageNefmtm1Ral/Nefmtm1Ralinvolves: 129S1/Sv * 129X1/SvJ
Nefhtm1Ral/Nefhtm1Ralinvolves: 129S1/Sv * 129X1/SvJ
Nefhtm1Ral/Nefhtm1Ral
Nefmtm1Ral/Nefmtm1Ral		involves: 129S1/Sv * 129X1/SvJ
Hind limb paralysis develops in two year old Nefmtm1Ral/Nefmtm1Ral Nefhtm1Ral/Nefhtm1Ral miceNefhtm1Ral/Nefhtm1Ral
Nefmtm1Ral/Nefmtm1Ral		involves: 129S1/Sv * 129X1/SvJ
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory