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Phenotype Images associated with this Allele
Nomenclature
Symbol: Cav1tm1Mls
Name: caveolin 1, caveolae protein; targeted mutation 1, Michael P Lisanti
MGI ID: MGI:2180364
Synonyms: cav-, Cav-1-, Cav-1 KO, Caveolin-1 KO, Cavtm1Mls
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lung endothelial cells in Cav1tm1Mls/Cav1tm1Mls mice lack caveolae and are more numerousCav1tm1Mls/Cav1tm1Mlsinvolves: 129/Sv * C57BL/6 * SJL
Caveolae formation is disrupted in Cav1tm1Mls/Cav1tm1Mls miceCav1tm1Mls/Cav1tm1Mlsinvolves: 129/Sv * C57BL/6 * SJL
Cav1tm1Mls/Cav1tm1Mls mice show lung abnormalities, with thickened alveolar septa and hypercellularityCav1tm1Mls/Cav1tm1Mlsinvolves: 129/Sv * C57BL/6 * SJL
Adipose tissue abnormalities in Cav1tm1Mls/Cav1tm1Mls mice
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory