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Phenotype Images associated with this Allele
Nomenclature
Symbol: Cav3tm1Mls
Name: caveolin 3; targeted mutation 1, Michael P Lisanti
MGI ID: MGI:2180558
Synonyms: cav-3-, CAV3 -
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Cav3tm1Mls/Cav3tm1Mls hearts display progressive left ventricular wall thickeningCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1Mls heart tissue displays cardiac myocyte hypertrophy, interstitial/peri-vascular fibrosis and cellular infiltratesCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1MlsFVB.Cg-Cav3tm1Mls
Cav3tm1Mls/Cav3tm1Mls skeletal muscle lacks sarcolemmal caveolaeCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1MlsFVB.Cg-Cav3tm1Mls
Cav3tm1Mls/Cav3tm1Mls skeletal muscle displays variable fiber size and some necrotic fibersCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1MlsFVB.Cg-Cav3tm1Mls
Abnormal T-tubule system in Cav3tm1Mls/Cav3tm1Mls skeletal muscleCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1MlsFVB.Cg-Cav3tm1Mls
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory