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Phenotype Images associated with this Allele
Nomenclature
Symbol: Flt4tm1Ali
Name: FMS-like tyrosine kinase 4; targeted mutation 1, Kari Alitalo
MGI ID: MGI:2181789
Synonyms: VEGFR-3-, Vegfr3lacZ, VEGFR-3/LacZ, Vegfr3lz
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Abnormal lymphatic development in Nrp2tm1Ddg/Nrp2+ Flt4tm1Ali/Flt4+ miceFlt4tm1Ali/Flt4+
Nrp2tm1Ddg/Nrp2+		involves: C57BL/6
Defective lymphatic sprouting in Nrp2tm1Ddg/Nrp2+ Flt4tm1Ali/Flt4+ and Nrp2tm1Ddg/Nrp2tm1Ddg miceFlt4tm1Ali/Flt4+
Nrp2tm1Ddg/Nrp2+		involves: C57BL/6
Nrp2tm1Ddg/Nrp2tm1Ddginvolves: C57BL/6
Tip cell abnormalities in Nrp2tm1Ddg/Nrp2+ Flt4tm1Ali/Flt4+ mice are similar to those obtained after anti-Nrp2B treatmentFlt4tm1Ali/Flt4+
Nrp2tm1Ddg/Nrp2+		involves: C57BL/6
Analysis of lymphatic structure and function in Nrp2tm1Ddg/Nrp2tm1Ddg and Nrp2tm1Ddg/Nrp2+ Flt4tm1Ali/Flt4+ miceFlt4tm1Ali/Flt4+
Nrp2tm1Ddg/Nrp2+		involves: C57BL/6
Nrp2tm1Ddg/Nrp2tm1Ddginvolves: C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory