Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ctsb^tm1Jde
Name:	cathepsin B; targeted mutation 1, Jan Deussing
MGI ID:	MGI:2182129
Synonyms:	Cat B^-, CathB^-, Ctsb^-, CTSB^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Cerebral and cerebellar atrophy in Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr mice	Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr	involves: 129P2/OlaHsd * C57BL/6J
	Apoptotic cell and neuron death in Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr mice	Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr	involves: 129P2/OlaHsd * C57BL/6J
	Accumulation of amorphous and membranous material in neuronal perikarya, dendrites, and axons in Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr mice	Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr	involves: 129P2/OlaHsd * C57BL/6J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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