Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Upk3a^tm1Tsun
Name:	uroplakin 3A; targeted mutation 1, Tung-Tien Sun
MGI ID:	MGI:2183244
Synonyms:	UPIII(-)

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Upk2^tm1Tsun/Upk2^tm1Tsun mice exhibit ureteral obstruction	Upk2^tm1Tsun/Upk2^tm1Tsun	involves: 129S/SvEv * Black Swiss
	Urothelium lacks the umbrella cells and is leaky in Upk3a^tm1Tsun/Upk3a^tm1Tsun mice	Upk3a^tm1Tsun/Upk3a^tm1Tsun	either: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
	Upk3a^tm1Tsun/Upk3a^tm1Tsun mice have an altered urothelial apical surface and enlarged ureteral orifice	Upk3a^tm1Tsun/Upk3a^tm1Tsun	either: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
	Upk3a^tm1Tsun/Upk3a^tm1Tsun urothelium lacks uroplakin-containing fusiform vesicles and normal, apical urothelial plaques	Upk3a^tm1Tsun/Upk3a^tm1Tsun	either: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
	Upk3a^tm1Tsun/Upk3a^tm1Tsun mice develop hydronephrosis and kidney abnormalities	Upk3a^tm1Tsun/Upk3a^tm1Tsun	either: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)

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