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Phenotype Images associated with this Allele
Nomenclature
Symbol: Cldn1tm1Sts
Name: claudin 1; targeted mutation 1, Shoichiro Tsukida
MGI ID: MGI:2183247
Synonyms: claudin-1-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Skin grafted from Cldn1tm1Sts/Cldn1tm1Sts mice to nude mice shows fewer and shorter hairs and the grafts are thicker than in wild-typeCldn1tm1Sts/Cldn1tm1Stsinvolves: 129S4/SvJae * C57BL/6
Cldn1tm1Sts/Cldn1tm1Sts mice show wrinkled skin and rapid postnatal lethalityCldn1tm1Sts/Cldn1tm1Stsinvolves: 129S4/SvJae * C57BL/6
Stratum corneum abnormalities in Cldn1tm1Sts/Cldn1tm1Sts miceCldn1tm1Sts/Cldn1tm1Stsinvolves: 129S4/SvJae * C57BL/6
Barrier function of tight junctions is severely affected in Cldn1tm1Sts/Cldn1tm1Sts epidermisCldn1tm1Sts/Cldn1tm1Stsinvolves: 129S4/SvJae * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory