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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ptentm1Mro
Name: phosphatase and tensin homolog; targeted mutation 1, Silvia Marino
MGI ID: MGI:2183284
Synonyms: Ptenfl, Ptenflox, Ptenfx, PtenLoxP
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Prostate cancer progression in Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+, Tg(Pbsn-cre)4Prb/0 Ptentm1Mro/Pten+, and Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ miceGt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+
Tg(Pbsn-cre)4Prb/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+
Ptentm1Mro/Pten+
Tg(Pbsn-cre)4Prb/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
Ptentm1Mro/Pten+
Tg(Pbsn-cre)4Prb/0		involves: C57BL/6 * DBA/2
Prostate lesions in Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+, Tg(Pbsn-cre)4Prb/0 Ptentm1Mro/Pten+, and Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ miceGt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+
Tg(Pbsn-cre)4Prb/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+
Ptentm1Mro/Pten+
Tg(Pbsn-cre)4Prb/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
Ptentm1Mro/Pten+
Tg(Pbsn-cre)4Prb/0		involves: C57BL/6 * DBA/2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory