Phenotype Images associated with this Transgene

Nomenclature

Symbol:	H2az2^{Tg(Wnt1-cre)11Rth}
Name:	H2A.Z histone variant 2; transgene insertion 11, David H Rowitch
MGI ID:	MGI:2386570
Synonyms:	Tg(Wnt1-cre)11Rth, Wnt1-Cre, Wnt1^Cre, Wnt1cre, Wnt1::Cre

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Evidence of inflammation in both the proximal and mid-colon of the Ednrb^tm1Nrd/Ednrb^tm1Nrd Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ H2az2^{Tg(Wnt1-cre)11Rth}/0 animals
	Peyer's Patches (PP) of Ednrb^tm1Nrd/Ednrb^tm1Nrd Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ H2az2^{Tg(Wnt1-cre)11Rth}/0 animals are small in size but have normal architecture
	The spleen of Ednrb^tm1Nrd/Ednrb^tm1Nrd Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ H2az2^{Tg(Wnt1-cre)11Rth}/0 animals is small in size and has abnormal architecture
	Reduced numbers of sympathetic and dorsal root ganglia neurons in Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/0 fetuses	Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * C57BL/6N * CBA/J
	Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/0 fetuses exhibit a decreased inferior facial angle and increased mandibular retroposition	Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * C57BL/6N * CBA/J
	Reduction in the number of TH+ neurons in the dorsal root ganglia of Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/0 embryos	Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * C57BL/6N * CBA/J
	Reduction in the number of TrkA+ fibers in the dorsal horn of the spinal cord and in the skin of Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi}H2az2^{Tg(Wnt1-cre)11Rth}/0 fetuses	Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * C57BL/6N * CBA/J
	Reduced sympathetic and parasympathetic innervation of the submandibular gland in Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/0 embryos	Elp1^{tm1c(KOMP)Wtsi}/Elp1^{tm1c(KOMP)Wtsi} H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * C57BL/6N * CBA/J
	Mandibular hypoplasia and cleft palate in Map3k7^tm1Mis/Map3k7^tm1MisH2az2^{Tg(Wnt1-cre)11Rth}/0 mice	Map3k7^tm1Mis/Map3k7^tm1Mis H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * CBA/J
	Palatal shelves of Map3k7^tm1Mis/Map3k7^tm1Mis H2az2^{Tg(Wnt1-cre)11Rth}/0 mice show delayed rugal formation	Map3k7^tm1Mis/Map3k7^tm1Mis H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: C57BL/6J * CBA/J
	Ror1^tm1.1Meg/Ror1^tm1.1Meg Ror2^tm1.1Meg/Ror2^tm1.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/0 embryos exhibit sympathetic axon branching defects	Ror1^tm1.1Meg/Ror1^tm1.1Meg Ror2^tm1.1Meg/Ror2^tm1.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: 129S4/SvJae * C57BL/6J * CBA/J
	Effects of Cre-mediated rescue of Chd7^Gt(XK403)Byg mutation on the arch artery phenotype at E10.5	Chd7^Gt(XK403)Byg/Chd7⁺	involves: 129P2/OlaHsd * C57BL/6
		Chd7^Gt(XK403)Byg/Chd7⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	either: (involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA/J) or (involves: 129P2/OlaHsd * C57BL/6J * CBA/J * CD-1)
		Chd7^Gt(XK403)Byg/Chd7⁺ Tg(Tbx1-cre)1Joe/0	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)
		Chd7^Gt(XK403)Byg/Chd7⁺ Tfap2a^tm1(cre)Moon/Tfap2a⁺	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)
	Craniofacial malformation in Ext1^tm1Yama/Ext1^tm1YamaH2az2^{Tg(Wnt1-cre)11Rth}/0 mice	Ext1^tm1Yama/Ext1^tm1Yama H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	B6.Cg-H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama
	Peters-like anomaly in Ext1^tm1Yama/Ext1^tm1Yama H2az2^{Tg(Wnt1-cre)11Rth}/0 mice	Ext1^tm1Yama/Ext1^tm1Yama H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	B6.Cg-H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama
	Neural crest cell proliferation in the anterior chamber of Ext1^tm1Yama/Ext1^tm1Yama H2az2^{Tg(Wnt1-cre)11Rth}/0 mice is disturbed	Ext1^tm1Yama/Ext1^tm1Yama H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	B6.Cg-H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama
	Thin cornea and iridocorneal dysgenesis in Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/0 Tgfb2^tm1Doe/Tgfb2⁺ mice	Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tgfb2^tm1Doe/Tgfb2⁺	B6.Cg-Tgfb2^tm1Doe H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama
	Aberrant iridocorneal development in Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/0 Tgfb2^tm1Doe/Tgfb2⁺ mice	Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tgfb2^tm1Doe/Tgfb2⁺	B6.Cg-Tgfb2^tm1Doe H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama
	Skeletal image of newborn Sox9^tm2Crm/Sox9^tm2Crm H2az2^{Tg(Wnt1-cre)11Rth}/0 mice	Sox9^tm2Crm/Sox9^tm2Crm H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: 129S7/SvEvBrd * C57BL/6 * CBA
	Skeletal preparations of wild-type and Sox9^tm2Crm/Sox9^tm2Crm H2az2^{Tg(Wnt1-cre)11Rth}/0 embryos	Sox9^tm2Crm/Sox9^tm2Crm H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺	involves: 129S7/SvEvBrd * C57BL/6 * CBA

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