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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ncoa6tm1Jkr
Name: nuclear receptor coactivator 6; targeted mutation 1, Janardan K Reddy
MGI ID: MGI:2448995
Synonyms: LoxP-PRIP
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Retarded ductal branching of Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(MMTV-cre)FMam/? mammary glands during pubertyNcoa6tm1Jkr/Ncoa6tm1Jkr
Tg(MMTV-cre)FMam/?		involves: 129P2/OlaHsd * FVB
Mammary glands of Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(MMTV-cre)FMam/? females have underdeveloped lobuloalveolar structures on the 15th day of pregnancyNcoa6tm1Jkr/Ncoa6tm1Jkr
Tg(MMTV-cre)FMam/?		involves: 129P2/OlaHsd * FVB
Defective development of lactating Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(MMTV-cre)FMam/? mammary glandsNcoa6tm1Jkr/Ncoa6tm1Jkr
Tg(MMTV-cre)FMam/?		involves: 129P2/OlaHsd * FVB
Ductal branching of Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(MMTV-cre)FMam/? mammary glands is attenuated in response to estrogen treatmentNcoa6tm1Jkr/Ncoa6tm1Jkr
Tg(MMTV-cre)FMam/?		involves: 129P2/OlaHsd * FVB
Increased apoptosis, but no change in proliferation, in terminal end buds of Ncoa6tm1Jkr/Ncoa6tm1Jkr Tg(MMTV-cre)FMam/? mammary glandsNcoa6tm1Jkr/Ncoa6tm1Jkr
Tg(MMTV-cre)FMam/?		involves: 129P2/OlaHsd * FVB
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory