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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dmp1tm1Mis
Name: dentin matrix protein 1; targeted mutation 1, Yuji Mishina
MGI ID: MGI:3040629
Synonyms: dmp1 KO, Dmp1tm1Jqf
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Abnormal tooth morphology and mineralization in Dmp1tm1Mis/Dmp1tm1Mis pupsDmp1tm1Mis/Dmp1tm1Misinvolves: 129S7/SvEvBrd * C57BL/6
Decreased dentin thickness and increased cavities of pulp and root canals in Dmp1tm1Mis/Dmp1tm1Mis miceDmp1tm1Mis/Dmp1tm1Misinvolves: 129S7/SvEvBrd * C57BL/6
Decreased mineralization is associated with altered dentin matrix structure in Dmp1tm1Mis/Dmp1tm1Mis miceDmp1tm1Mis/Dmp1tm1Misinvolves: 129S7/SvEvBrd * C57BL/6
Dmp1tm1Mis/Dmp1tm1Mis mice exhibit defects in the maturation of predentin to dentinDmp1tm1Mis/Dmp1tm1Misinvolves: 129S7/SvEvBrd * C57BL/6
The third molar is either missing or retarded in Dmp1tm1Mis/Dmp1tm1Mis miceDmp1tm1Mis/Dmp1tm1Misinvolves: 129S7/SvEvBrd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory