About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Nr4a2tm1Omc
Name: nuclear receptor subfamily 4, group A, member 2; targeted mutation 1, Orla M Conneely
MGI ID: MGI:3043985
Synonyms: Nurr1-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Tyrosine hydroxylase (TH) expression shows that differentiation to the dopaminergic phenotype in the ventral brain fails to occur at E11.5 in Nr4a2tm1Omc/Nr4a2tm1Omc embryosNr4a2tm1Omc/Nr4a2tm1Omcinvolves: 129S7/SvEvBrd * C57BL/6
Nr4a2tm1Omc/Nr4a2tm1Omcinvolves: 129S7/SvEvBrd
Loss of Ptx3 expression and increased cell death in ventral midbrain region of newborn Nr4a2tm1Omc/Nr4a2tm1Omc miceNr4a2tm1Omc/Nr4a2tm1Omcinvolves: 129S7/SvEvBrd * C57BL/6
Absence of dopaminergic markers in the ventral midbrain of Nr4a2tm1Omc/Nr4a2tm1Omc miceNr4a2tm1Omc/Nr4a2tm1Omcinvolves: 129S7/SvEvBrd * C57BL/6
Nr4a2tm1Omc/Nr4a2tm1Omcinvolves: 129S7/SvEvBrd
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory