Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Prkar1a^tm1.2Lsk
Name:	protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1.2, Lawrence Kirschner
MGI ID:	MGI:3512112
Synonyms:	Prkar1a^loxP

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Prkar1a heterozygosity accelerates osteosarcoma development in Tg(Bglap2-TAg)1Rkho/0 mice	Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Bglap2-TAg)1Rkho/0 Tg(Col1a1-cre)1Kry/0	involves: 129S1/Sv * 129X1/SvJ * FVB/N
		Tg(Bglap2-TAg)1Rkho/0	FVB/N-Tg(Bglap2-TAg)1Rkho
	Bone tumorigenesis nd abundant osteoclasts in Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Col1a1-cre)1Kry/0 mice	Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Bglap2-TAg)1Rkho/0 Tg(Col1a1-cre)1Kry/0	involves: 129S1/Sv * 129X1/SvJ * FVB/N
		Tg(Bglap2-TAg)1Rkho/0	FVB/N-Tg(Bglap2-TAg)1Rkho
		Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Col1a1-cre)1Kry/0	involves: 129S1/Sv * 129X1/SvJ * FVB/N
	Osteosarcoma characterization in Tg(Bglap2-TAg)1Rkho/0 and Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Col1a1-cre)1Kry/0 Tg(Bglap2-TAg)1Rkho/0 mice	Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Bglap2-TAg)1Rkho/0 Tg(Col1a1-cre)1Kry/0	involves: 129S1/Sv * 129X1/SvJ * FVB/N
		Tg(Bglap2-TAg)1Rkho/0	FVB/N-Tg(Bglap2-TAg)1Rkho

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24