About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Abca12tm1Lex
Name: ATP-binding cassette, sub-family A member 12; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3528440
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Neonatal lethality and epidermal hyperkeratosis in Abca12tm1Lex/Abca12tm1Lex miceAbca12tm1Lex/Abca12tm1Lexinvolves: 129S/SvEvBrd * C57BL/6J
Abca12tm1Lex/Abca12tm1Lex mice fail to develop the epidermal permeability barrierAbca12tm1Lex/Abca12tm1Lexinvolves: 129S/SvEvBrd * C57BL/6J
Hyperkeratosis of the stratum corneum and disrupted interstitial lamellar lipid structure in Abca12tm1Lex/Abca12tm1Lex miceAbca12tm1Lex/Abca12tm1Lexinvolves: 129S/SvEvBrd * C57BL/6J
Abca12tm1Lex/Abca12tm1Lex P0 pups are able to inflate their lungs if maintained in a hydrating environmentAbca12tm1Lex/Abca12tm1Lexinvolves: 129S/SvEvBrd * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory