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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lmnatm1Lgf
Name: lamin A; targeted mutation 1, Loren G Fong
MGI ID: MGI:3587791
Synonyms: LmnaHG
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Misshapen nuclei in Lmnatm4Lgf/Lmna+ and Lmnatm1Lgf/Lmna+ MEFsLmnatm1Lgf/Lmna+involves: 129P2/OlaHsd * C57BL/6
Lmnatm4Lgf/Lmna+involves: 129P2/OlaHsd * C57BL/6
Rib fractures in Lmnatm4Lgf/Lmna+ and Lmnatm1Lgf/Lmna+ miceLmnatm1Lgf/Lmna+involves: 129P2/OlaHsd * C57BL/6
Lmnatm4Lgf/Lmna+involves: 129P2/OlaHsd * C57BL/6
Lmnatm1Lgf/Lmna+ mice show reduced survival, lose weight, and have decreased subcutaneous and abndominal fatLmnatm1Lgf/Lmna+involves: 129P2/OlaHsd * C57BL/6
Lmnatm1Lgf/Lmna+ mice exhibt kyphosis, rib fractures, and skull abnormalitiesLmnatm1Lgf/Lmna+involves: 129P2/OlaHsd * C57BL/6
Lmnatm1Lgf/Lmnatm1Lgf mice are small and have poorly mineralized boneLmnatm1Lgf/Lmnatm1Lgfinvolves: 129P2/OlaHsd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory