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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lama1tm1Olf
Name: laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
MGI ID: MGI:3611212
Synonyms: Lama1flox
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice have a similar but more severe retinal phenotype than Lama1nmf223/Lama1nmf223 miceLama1tm1Olf/Lama1tm1Olf
Edil3Tg(Sox2-cre)1Amc/Edil3+		involves: 129S2/SvPas * C57BL/6J * CBA * CD-1 * Swiss Webster
Peripheral retinal degeneration is observed in Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice as early as 4 weeks of ageLama1tm1Olf/Lama1tm1Olf
Edil3Tg(Sox2-cre)1Amc/Edil3+		involves: 129S2/SvPas * C57BL/6J * CBA * CD-1 * Swiss Webster
The inner limiting membrane does not form in Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 miceLama1tm1Olf/Lama1tm1Olf
Edil3Tg(Sox2-cre)1Amc/Edil3+		involves: 129S2/SvPas * C57BL/6J * CBA * CD-1 * Swiss Webster
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory