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Phenotype Images associated with this Allele
Nomenclature
Symbol: Pnpla2tm1Rze
Name: patatin-like phospholipase domain containing 2; targeted mutation 1, Rudolf Zechner
MGI ID: MGI:3629035
Synonyms: ATGL-, ATGL-ko
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Increase in neutral lipid content in Abhd5tm1.1Rze/Abhd5tm1.1Rze and Pnpla2tm1Rze/Pnpla2tm1Rze liversAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6
Pnpla2tm1Rze/Pnpla2tm1Rzeinvolves: 129P2/OlaHsd
Disrupted epidermal permeability barrier and impaired keratinocyte differentiation in Abhd5tm1.1Rze/Abhd5tm1.1Rze mice but not Pnpla2tm1Rze/Pnpla2tm1Rze miceAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6
Pnpla2tm1Rze/Pnpla2tm1Rzeinvolves: 129P2/OlaHsd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory