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Phenotype Images associated with this Allele
Nomenclature
Symbol: Gnai3tm1Lbi
Name: G protein subunit alpha i3; targeted mutation 1, Lutz Birnbaumer
MGI ID: MGI:3652743
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Rib and sternum defects in mice with mutations of Gnai1, Gnai2, and/or Gnai3Gnai1tm1Drs/Gnai1tm1Drs
Gnai3tm1Lbi/Gnai3tm1Lbi
involves: 129S/SvEv
Gnai3tm1Lbi/Gnai3tm1Lbiinvolves: 129S/SvEv
Gnai1tm1Drs/Gnai1+
Gnai3tm1Lbi/Gnai3tm1Lbi
involves: 129S/SvEv
Gnai2tm1Lbi/Gnai2+
Gnai3tm1Lbi/Gnai3tm1Lbi
involves: 129S/SvEv * 129S7/SvEvBrd
Gnai1tm1Drs/Gnai1tm1Drs
Gnai2tm1Lbi/Gnai2tm1Lbi
involves: 129S7/SvEvBrd
Fusion of lumbar vertebrae in Gnai3tm1Lbi/Gnai3tm1Lbi miceGnai3tm1Lbi/Gnai3tm1Lbiinvolves: 129S/SvEv * C57BL/6
Gnai3tm1Lbi/Gnai3tm1Lbiinvolves: 129S/SvEv
Rib fusion phenotype is enhanced in Gnai3tm1Lbi/Gnai3tm1Lbi mice by loss of Gnai2 in cartilageGnai2tm2.1Lbi/Gnai2tm2.1Lbi
Gnai3tm1Lbi/Gnai3tm1Lbi
Sox9tm3(cre)Crm/Sox9+
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6
Gnai2tm2.1Lbi/Gnai2tm2.1Lbi
Gnai3tm1Lbi/Gnai3tm1Lbi
Tg(Myog-cre)1Eno/0
involves: 129S/SvEv * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory