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Phenotype Images associated with this Allele
Nomenclature
Symbol: Bmp2tm1Cjt
Name: bone morphogenetic protein 2; targeted mutation 1, Clifford J Tabin
MGI ID: MGI:3699309
Synonyms: Bmp2c
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mice deficient singly or in various combinations of Bmp2, Bmp4 and Bmp7 display limb defectsBmp2tm1Cjt/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4+
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * SJL
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp7tm1Rob/Bmp7tm1Rob
Tg(Prrx1-cre)1Cjt/0		involves: 129S/SvEv * C57BL/6 * SJL
Mice lacking Bmp2 in the limbs exhibit syndactylyBmp2tm1Cjt/Bmp2tm1Cjt
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * SJL
Osteogenesis begins during early embryonic development in mice lacking Bmp2 and Bmp4 in the limbsBmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Defects in bone formation in mice lacking Bmp2 and Bmp4 in the limbsBmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Limb syndactyly in mice lacking Bmp2 and Bmp4Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory