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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Col2a1-PTHLH)2Ecw
Name: transgene insertion 2, Eleanor C Weir
MGI ID: MGI:3717404
Synonyms: col II-PTHrP
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Skeletal phenotypes of wild type, Tg(Col2a1-PTHLH)2Ecw/0, Pthlhtm1Hmk/Pthlhtm1Hmk, and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 miceTg(Col2a1-PTHLH)2Ecw/0involves: C57BL/6 * SJL
Pthlhtm1Hmk/Pthlhtm1Hmkinvolves: 129S2/SvPas
Pthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Gross appearance of Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 micePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Skull comparison of wild-type and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 micePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Radiographic analysis of tooth eruption in wild-type littermates and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 micePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Tooth histology of a wild-type littermate and a Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 neonatePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Dental phenotype of Pthlhtm1Hmk/Pthlhtm1Hmk mice rescued with Tg(Col2a1-PTHLH)2Ecw and Tg(KRT14-PTHLH)7Wmp transgenesPthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
Tg(KRT14-PTHLH)7Wmp/0
involves: 129S2/SvPas * C57BL/6 * SJL

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory