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Phenotype Images associated with this Allele
Nomenclature
Symbol: Gab1tm4Wbm
Name: growth factor receptor bound protein 2-associated protein 1; targeted mutation 4, Walter Birchmeier
MGI ID: MGI:3759866
Synonyms: Gab1deltaPI3K (Y448F/Y473F/Y590F)
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Gab1tm4Wbm/Gab1tm4Wbm mice have open eyelids at birth and keratinocytes show impaired wound closure in vitroGab1tm4Wbm/Gab1tm4Wbminvolves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1
Cleft palate in Gab1tm3Wbm/Gab1tm3Wbm, Gab1tm2Wbm/Gab1tm2Wbm, Gab1tm1Wbm/Gab1tm1Wbm and Gab1tm3Wbm/Gab1tm3Wbm Mettm1Cbm/Met+ mice, but not in Gab1tm4Wbm/Gab1tm4Wbm miceGab1tm1Wbm/Gab1tm1Wbminvolves: 129P2/OlaHsd * C57BL/6 * CD-1
Gab1tm4Wbm/Gab1tm4Wbminvolves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1
Gab1tm3Wbm/Gab1tm3Wbminvolves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1
Gab1tm3Wbm/Gab1tm3Wbm
Mettm1Cbm/Met+
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1
Gab1tm2Wbm/Gab1tm2Wbminvolves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory