Phenotype Images associated with this Transgene - MGI

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Phenotype Images associated with this Transgene

Nomenclature

Symbol:	Tg(Itgax-cre)1-1Reiz
Name:	transgene insertion 1-1, Boris Reizis
MGI ID:	MGI:3763248
Synonyms:	Cd11c-cre, CD11cCre, CD11cCre^T

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Lupus-like autoimmune disease in Lyn^tm1Sor/Lyn^tm1Sor and Lyn^tm1.1Calo/Lyn^tm1.1Calo Top2a^{Gt(PST14568)Mfgc}/0 mice	Lyn^tm1Sor/Lyn^tm1Sor	involves: 129S4/SvJaeSor
		Lyn^tm1.1Calo/Lyn^tm1.1Calo Tg(Itgax-cre)1-1Reiz/0	involves: 129P2/OlaHsd * C57BL/6 * CBA
	By 8 months, severe leukocyte infiltration is seen in the lungs, liver and skin of Lyn^tm1Sor/Lyn^tm1Sor mice but not Lyn^tm1.1Calo/Lyn^tm1.1Calo Tg(Itgax-cre)1-1Reiz/0 mice	Lyn^tm1Sor/Lyn^tm1Sor	involves: 129S4/SvJaeSor
		Lyn^tm1.1Calo/Lyn^tm1.1Calo Tg(Itgax-cre)1-1Reiz/0	involves: 129P2/OlaHsd * C57BL/6 * CBA
	Splenomegaly and lymphadenopathy in Lyn^tm1Sor/Lyn^tm1Sor and Lyn^tm1.1Calo/Lyn^tm1.1Calo Tg(Itgax-cre)1-1Reiz/0 mice	Lyn^tm1Sor/Lyn^tm1Sor	involves: 129S4/SvJaeSor
		Lyn^tm1.1Calo/Lyn^tm1.1Calo Tg(Itgax-cre)1-1Reiz/0	involves: 129P2/OlaHsd * C57BL/6 * CBA

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