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Phenotype Images associated with this Allele
Nomenclature
Symbol: Zfpm2tm2Sho
Name: zinc finger protein, multitype 2; targeted mutation 2, Stuart Orkin
MGI ID: MGI:3802480
Synonyms: Fog2flox
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Abnormal heart development and coronary vasculogenesis in Nkx2-5tm1(cre)Rjs/Nkx2-5+ Zfpm2tm1Sho/Zfpm2tm2Sho miceZfpm2tm1Sho/Zfpm2tm2Sho
Nkx2-5tm1(cre)Rjs/Nkx2-5+		involves: 129S1/Sv * 129S7/SvEvBrd
Dilated cardiomyopathy in Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Myh6-cre)2182Mds/0 miceZfpm2tm1Sho/Zfpm2tm2Sho
Tg(Myh6-cre)2182Mds/0		involves: 129S1/Sv * 129S7/SvEvBrd
Defective myocardial perfusion and coronary vasculature in adult Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Myh6-cre)2182Mds/0 heartZfpm2tm1Sho/Zfpm2tm2Sho
Tg(Myh6-cre)2182Mds/0		involves: 129S1/Sv * 129S7/SvEvBrd
Decreased density of coronary blood vessels in doxycycline-treated Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Tnnt2-rtTA,tetO-cre)1Wtp/0 heartsZfpm2tm1Sho/Zfpm2tm2Sho
Tg(Tnnt2-rtTA,tetO-cre)1Wtp/0		involves: 129S1/Sv * 129S7/SvEvBrd
Increased fibrotic tissues in doxycycline-treated Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Tnnt2-rtTA,tetO-cre)1Wtp/0 heartsZfpm2tm1Sho/Zfpm2tm2Sho
Tg(Tnnt2-rtTA,tetO-cre)1Wtp/0		involves: 129S1/Sv * 129S7/SvEvBrd
Paucity of coronary vessels in Zfpm2tm1Sho/Zfpm2tm2Sho Nkx2-5tm1(cre)Rjs/Nkx2-5+ heartsZfpm2tm1Sho/Zfpm2tm2Sho
Nkx2-5tm1(cre)Rjs/Nkx2-5+		involves: 129S1/Sv * 129S7/SvEvBrd
Increased fibrosis in Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Myh6-cre)2182Mds/0 heartsZfpm2tm1Sho/Zfpm2tm2Sho
Tg(Myh6-cre)2182Mds/0		involves: 129S1/Sv * 129S7/SvEvBrd
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory