Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Nhej1^tm1Fwa
Name:	non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt
MGI ID:	MGI:3809930
Synonyms:	Cernunnos-XLF, Xlf^-, XLF, XLF^delta

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Small body size, absence of thymus, and small spleen in Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa mice	Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa	involves: 129S6/SvEvTac * C57BL/6NTac
	Small size, much smaller spleens and drastic involution of the thymus in Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa mice	Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa	involves: 129S6/SvEvTac * C57BL/6NTac
	Increased genomic instability and apoptosis in the central nervous system of Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa embryos	Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa	involves: 129S6/SvEvTac * C57BL/6NTac
	Small body size, small spleen and absent thymus in Nhej1^tm1Fwa/Nhej1^tm1Fwa Xrcc5^tm1Nus/Xrcc5^tm1Nus mice	Nhej1^tm1Fwa/Nhej1^tm1Fwa Xrcc5^tm1Nus/Xrcc5^tm1Nus	involves: 129S6/SvEvTac * C57BL/6
	Small size of 5-day old Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa (arow) mouse	Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa	involves: 129S6/SvEvTac * C57BL/6NTac

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