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Phenotype Images associated with this Allele
Nomenclature
Symbol: Trpm7tm1Clph
Name: transient receptor potential cation channel, subfamily M, member 7; targeted mutation 1, David E Clapham
MGI ID: MGI:3814705
Synonyms: Trpm7fl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Representative images of grossly deformed, nonviable Trpm7tm1Clph/Trpm7tm1Clph Tg(CAG-cre/Esr1*)5Amc/0 embryos at E9.5 and E10.5Trpm7tm1Clph/Trpm7tm1Clph
Tg(CAG-cre/Esr1*)5Amc/0		involves: 129S4/SvJae * C57BL/6 * CBA
Small kidney, kidney cysts, and reduced number of glomeruli in Trpm7tm1Clph/Trpm7tm1Clph Tg(Pax3-cre)1Joe/0 miceTrpm7tm1Clph/Trpm7tm1Clph
Tg(Pax3-cre)1Joe/0		involves: 129S4/SvJae * C57BL/6 * SJL
Early defective nephrogenesis and progressive kidney failure in Trpm7tm1Clph/Trpm7tm1Clph Tg(Pax3-cre)1Joe/0 miceTrpm7tm1Clph/Trpm7tm1Clph
Tg(Pax3-cre)1Joe/0		involves: 129S4/SvJae * C57BL/6 * SJL
Loss of pigment in the lower trunk of Trpm7tm1Clph/Trpm7tm1Clph Tg(Pax3-cre)1Joe/0 miceTrpm7tm1Clph/Trpm7tm1Clph
Tg(Pax3-cre)1Joe/0		involves: 129S4/SvJae * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory