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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sgpl1tm1(SGPL1)Lex
Name: sphingosine phosphate lyase 1; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3833933
Synonyms: S1PLH
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Heart and urinary bladder abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex mice and bone and urinary bladder abnormalities in Sgpl1tm1(SGPL1)Lex/Sgpl1Gt(OST58278)Lex miceSgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Sgpl1Gt(OST58278)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Thymus abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex, Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lex and Sgpl1tm1(SGPL1)Lex/Sgpl1Gt(OST58278)Lex miceSgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S4/SvJae * 129S5/SvEvBrd * C57BL/6J
Sgpl1Gt(OST58278)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Mesenteric lymph node abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex, Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lex and Sgpl1tm1(SGPL1)Lex/Sgpl1Gt(OST58278)Lex miceSgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S4/SvJae * 129S5/SvEvBrd * C57BL/6J
Sgpl1Gt(OST58278)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Spleen abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex mice but not Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lex and Sgpl1tm1(SGPL1)Lex/Sgpl1Gt(OST58278)Lex miceSgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S4/SvJae * 129S5/SvEvBrd * C57BL/6J
Sgpl1Gt(OST58278)Lex/Sgpl1tm1(SGPL1)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Lung abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex miceSgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lexinvolves: 129S5/SvEvBrd * C57BL/6J
Bone abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex miceSgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lexinvolves: 129S5/SvEvBrd * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory