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Phenotype Images associated with this Allele
Nomenclature
Symbol: GlmpGt(P084H04)Wrst
Name: glycosylated lysosomal membrane protein; gene trap P084H04, German Gene Trap Consortium
MGI ID: MGI:3865377
Synonyms: Ncu-g1gt
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Liver fibrosis and splenomegaly in GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst miceGlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrstinvolves: 129S2/SvPas * C57BL/6
Inflammation, dying hepatocytes and collagen deposition in GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst liverGlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrstinvolves: 129S2/SvPas * C57BL/6
Increased rate of cell death in GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst liverGlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrstinvolves: 129S2/SvPas * C57BL/6
Activated fibrogenic response in GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst liverGlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrstinvolves: 129S2/SvPas * C57BL/6
Intralysosomal accumulation of lipofuscin and iron in GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst Kupffer cellsGlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrstinvolves: 129S2/SvPas * C57BL/6
Massive activation/proliferation of the oval cells in GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst liverGlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrstinvolves: 129S2/SvPas * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory