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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mob1bGt(CC0690)Wtsi
Name: MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute
MGI ID: MGI:3870385
Synonyms: Mob1btr
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Tumorgenesis in Mob1atm1.2Asuz/Mob1atm1.2Asuz Mob1bGt(CC0690)Wtsi/Mob1b+ or Mob1atm1.2Asuz/Mob1a+ Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.2Asuz/Mob1atm1.2Asuz
Mob1bGt(CC0690)Wtsi/Mob1b+		involves: 129P2/OlaHsd * C57BL/6
Mob1atm1.2Asuz/Mob1a+
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi		involves: 129P2/OlaHsd * C57BL/6
Skin and hair abnormalities and large paws in tamoxifen treated Mob1atm1.1Asuz/Mob1atm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * C57BL/6 * CD-1
Increased proliferation, repressed apoptosis, and impaired contact inhibition and chromosome segregation in Mob1atm1.1Asuz/Mob1atm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi keratinocytesMob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * C57BL/6 * CD-1
Skin cancer in Mob1atm1.2Asuz/Mob1atm1.2Asuz Mob1bGt(CC0690)Wtsi/Mob1b+ and Mob1atm1.2Asuz/Mob1a+ Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.2Asuz/Mob1atm1.2Asuz
Mob1bGt(CC0690)Wtsi/Mob1b+		involves: 129P2/OlaHsd * C57BL/6
Mob1atm1.2Asuz/Mob1a+
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi		involves: 129P2/OlaHsd * C57BL/6
Dental malocclusion, disorganized hair bundles, and increased trabeculae number in femoral bone of Mob1atm1.2Asuz/Mob1a+ Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.2Asuz/Mob1a+
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi		involves: 129P2/OlaHsd * C57BL/6
Hair follicle and interfollicular epidermis hyperplasia in tamoxifen treated Mob1atm1.1Asuz/Mob1atm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * C57BL/6 * CD-1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory