About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Cops6Gt(RRI087)Byg
Name: COP9 signalosome subunit 6; gene trap RRI087, BayGenomics
MGI ID: MGI:4128701
Synonyms: Csn6-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg mice die by E8.5Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byginvolves: 129P2/OlaHsd * C57BL/6J
Increase in gamma-irradiation-induced apoptosis in Cops6Gt(RRI087)Byg/Cops6+ thymus and developing central nervous systemCops6Gt(RRI087)Byg/Cops6+involves: 129P2/OlaHsd * C57BL/6J
Inhibition of gamma-irradiation induced tumorigenesis in Cops6Gt(RRI087)Byg/Cops6+ miceCops6Gt(RRI087)Byg/Cops6+involves: 129P2/OlaHsd * C57BL/6J
The embryonic lethality of Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg mice can be partially rescued by concomitant loss of Trp53Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg
Trp53tm1Glo/Trp53tm1Glo		involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory