Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Akr1a1^{Gt(OST222400)Lex}
Name:	aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics
MGI ID:	MGI:4239556
Synonyms:	GR^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Severe loss of bone and fractures in the long bones of Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} mice	Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex}	B6.129S5-Akr1a1^{Gt(OST222400)Lex}
	Spontaneous bone fractures and loss of trabecular bone in Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} mice	Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex}	B6.129S5-Akr1a1^{Gt(OST222400)Lex}
	Trabecular bone loss in castrated Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} males	Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex}	B6.129S5-Akr1a1^{Gt(OST222400)Lex}
	Affected turbinates in castrated Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} males	Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex}	B6.129S5-Akr1a1^{Gt(OST222400)Lex}
	"Rachitic rosary" phenotype of Gulo^tm1Mae/Gulo^tm1Mae and Akr1b1^tm1.1Kgab/Akr1b1^tm1.1Kgab Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} bones	Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} Akr1b1^tm1.1Kgab/Akr1b1^tm1.1Kgab	B6.Cg-Akr1a1^{Gt(OST222400)Lex} Akr1b1^tm1.1Kgab
		Gulo^tm1Mae/Gulo^tm1Mae	involves: C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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