Phenotype Images associated with this Allele
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Nomenclature
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Symbol:
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Ryr1tm1.1Dhm
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Name:
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ryanodine receptor 1, skeletal muscle;
targeted mutation 1.1, David H MacLennan
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MGI ID:
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MGI:4418317
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Synonyms:
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Ryr1I4895T,
Ryr1IT
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Images for
Allele
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Click images for details
 | Kyphosis, hindlimb paresis and myofiber abnormalities in Ryr1tm1.1Dhm/Ryr1+ mice | Ryr1tm1.1Dhm/Ryr1+ | involves: 129S2/SvPasCrl * 129S6/SvEvTac |
 | Soleus myofiber abnormalities in Ryr1tm1.1Dhm/Ryr1+ mice | Ryr1tm1.1Dhm/Ryr1+ | involves: 129S2/SvPasCrl * 129S6/SvEvTac |
 | Type 1 myofiber abnormalities in Ryr1tm1.1Dhm/Ryr1+ mouse | Ryr1tm1.1Dhm/Ryr1+ | involves: 129S2/SvPasCrl * 129S6/SvEvTac |
 | Ryr1tm1.1Dhm/Ryr1+ newborns are weak and cyanotic and mice exhibit congenital myopathy | Ryr1tm1.1Dhm/Ryr1+ | involves: 129S2/SvPasCrl * 129S6/SvEvTac |
 | Soleus muscle from Ryr1tm1.1Dhm/Ryr1+ mice shows variable fiber size and mild endomysial fibrosis | Ryr1tm1.1Dhm/Ryr1+ | involves: 129S2/SvPasCrl * 129S6/SvEvTac |
 | Small size, abnormal posture, reduced skeletal muscle bulk, myotube abnormalities, and underdeveloped dermis in Ryr1tm1.1Dhm/Ryr1tm1.1Dhm neonates | Ryr1tm1.1Dhm/Ryr1tm1.1Dhm | involves: 129S6/SvEvTac * 129X1/SvJ |
 | Delayed ossification and cardiac development, subcutaneous edema, and an atrial septal closure defect in Ryr1tm1.1Dhm/Ryr1tm1.1Dhm fetuses | Ryr1tm1.1Dhm/Ryr1tm1.1Dhm | involves: 129S6/SvEvTac * 129X1/SvJ |
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