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Phenotype Images associated with this Allele
Nomenclature
Symbol: Klf5tm2.1Rng
Name: Kruppel-like transcription factor 5; targeted mutation 2.1, Ryozo Nagai
MGI ID: MGI:4421792
Synonyms: Klf5fl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Cardiomyocyte-specific deletion of Klf5 does not alter pressure overload-induced hypertrophy in Klf5tm2.1Rng/Klf5tm2.1Rng Tg(Myh6-cre)2182Mds/0 miceKlf5tm2.1Rng/Klf5tm2.1Rng
Tg(Myh6-cre)2182Mds/0		involves: C57BL/6 * FVB/N
Fibroblast-specific deletion of Klf5 attenuates cardiac hypertrophy and fibrosis after TAC in Klf5tm2.1Rng/Klf5tm2.1Rng Tg(Postn-cre)1Sjc miceKlf5tm2.1Rng/Klf5tm2.1Rng
Tg(Postn-cre)1Sjc/0		involves: C57BL/6
Klf5tm2.1Rng/Klf5tm2.1Rng Tg(Postn-cre)1Sjc mice exhibit increased susceptibility to high-intensity transverse aortic constrictionKlf5tm2.1Rng/Klf5tm2.1Rng
Tg(Postn-cre)1Sjc/0		involves: C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory