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Phenotype Images associated with this Allele
Nomenclature
Symbol: Porcntm1.1Lcm
Name: porcupine O-acyltransferase; targeted mutation 1.1, Lewis Murtaugh
MGI ID: MGI:4429133
Synonyms: Porcn-2lox, Porcn-lox
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Focal dermal hypoplasia-like phenotypes in Porcntm1.1Lcm/Porcn+ Edil3Tg(Sox2-cre)1Amc/0 embryosPorcntm1.1Lcm/Porcn+
Edil3Tg(Sox2-cre)1Amc/Edil3+		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Focal absence of hair follicles in Porcntm1.1Lcm/Porcn+ Edil3Tg(Sox2-cre)1Amc/0 micePorcntm1.1Lcm/Porcn+
Edil3Tg(Sox2-cre)1Amc/Edil3+		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Tissue-specific Porcntm1.1Lcm deletion phenotypes include skeletal defects and skin abnormalitiesPorcntm1.1Lcm/Y
Tg(Prrx1-cre)1Cjt/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL/J
Porcntm1.1Lcm/Y
Tg(Msx2-cre)5Rem/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Focal absence of hair follicles in Porcntm1.1Lcm/Porcn+ Edil3Tg(Sox2-cre)1Amc/0 mice but normal keratinocyte differentiationPorcntm1.1Lcm/Porcn+
Edil3Tg(Sox2-cre)1Amc/Edil3+		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory