Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Mcph1^tm1.2Kali
Name:	microcephaly, primary autosomal recessive 1; targeted mutation 1.2, Kaiyi Li
MGI ID:	MGI:4429492
Synonyms:	BRIT1^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mcph1^tm1.2Kali/Mcph1^tm1.2Kali males are infertile and exhibit meiotic defects	Mcph1^tm1.2Kali/Mcph1^tm1.2Kali	involves: 129S7/SvEvBrd * C57BL/6J
	Meiosis in Mcph1^tm1.2Kali/Mcph1^tm1.2Kali spermatocytes is arrested prior to the pachytene stage with aberrant chromosomal synapsis	Mcph1^tm1.2Kali/Mcph1^tm1.2Kali	involves: 129S7/SvEvBrd * C57BL/6J
	Recombination DNA repair was impaired in Mcph1^tm1.2Kali/Mcph1^tm1.2Kali spermatocytes	Mcph1^tm1.2Kali/Mcph1^tm1.2Kali	involves: 129S7/SvEvBrd * C57BL/6J
	Mcph1^tm1.2Kali/Mcph1^tm1.2Kali ovaries are small and have no ovarian follicles	Mcph1^tm1.2Kali/Mcph1^tm1.2Kali	involves: 129S7/SvEvBrd * C57BL/6J

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