About   Help   FAQ
Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Notch3*R169C)88Bbb
Name: transgene insertion 88, Norbert Hubner
MGI ID: MGI:4429538
Synonyms: TgNotch3R169C
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Tg(Notch3*R169C)88Bbb/0 mice exhibit granular osmiophilic material deposits in smooth muscle cellsTg(Notch3*R169C)88Bbb/0involves: FVB/N
White matter lesions and astrogliosis in aged Tg(Notch3*R169C)88Bbb/0 miceTg(Notch3*R169C)88Bbb/0involves: FVB/N
Arterial structure is preserved, but capillary density is progressively reduced in the white matter of Tg(Notch3*R169C)88Bbb/0 miceTg(Notch3*R169C)88Bbb/0involves: FVB/N
Vacuolization of the white matter in 20 month-old Tg(Notch3*R169C)88Bbb/0 miceTg(Notch3*R169C)88Bbb/0involves: FVB/N
20 month-old Tg(Notch3*R169C)88Bbb/0 mice exhibit white matter damage and astrogliosis in the hippocampusTg(Notch3*R169C)88Bbb/0involves: FVB/N
Progressive astrogliosis in the white matter of Tg(Notch3*R169C)88Bbb/0 mice prior to white matter disorganization and vacuolizationTg(Notch3*R169C)88Bbb/0involves: FVB/N
Tg(Notch3*R169C)88Bbb/0 mice exhibit reductions of blood flow in the brain gray and white matterTg(Notch3*R169C)88Bbb/0involves: FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory