Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Robo3^tm1.1Ache
Name:	roundabout guidance receptor 3; targeted mutation 1.1, Alain Chedotal
MGI ID:	MGI:4441335
Synonyms:	Robo3^cko, Robo3^lox

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Reduction of commissural projections in r3 and r5 of Robo3^tm1.1Ache/Robo3^tm1.1Ache Egr2^tm2(cre)Pch/Egr2⁺ embryos	Egr2^tm2(cre)Pch/Egr2⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S2/SvPas
	Reduced internuclear commissure in Robo3^tm1.1Ache/Robo3^tm1.1Ache Egr2^tm2(cre)Pch/Egr2⁺ mice	Egr2^tm2(cre)Pch/Egr2⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S2/SvPas
	Uncrossed anterior vestibular cochlear nucleus-median nucleus of the trapezoid body projections in Robo3^tm1.1Ache/Robo3^tm1.1Ache Egr2^tm2(cre)Pch/Egr2⁺ mice	Egr2^tm2(cre)Pch/Egr2⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S2/SvPas
	Ataxic gait in Robo3^tm1.1Ache/Robo3^tm1.1Ache Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ mice	Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
	Fewer inferior olivary neurons project contralaterally in Robo3^tm1.1Ache/Robo3^tm1.1Ache Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ mice	Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
	Reduced internuclear commissure in Robo3^tm1.1Ache/Robo3^tm1.1Ache Egr2^tm2(cre)Pch/Egr2⁺ and Robo3^tm1Matl/Robo3^tm1Matl mice	Egr2^tm2(cre)Pch/Egr2⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S2/SvPas
		Robo3^tm1Matl/Robo3^tm1Matl	Not Specified
	The structure of the inferior olivary nucleus is disorganized in Robo3^tm1.1Ache/Robo3^tm1.1Ache Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ mice	Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

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