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Phenotype Images associated with this Allele
Nomenclature
Symbol: Abhd5tm1.1Rze
Name: abhydrolase domain containing 5; targeted mutation 1.1, Rudolf Zechner
MGI ID: MGI:4456205
Synonyms: Cgi-58-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Small size, glossy dry skin, and necrotic tail tip in Abhd5tm1.1Rze/Abhd5tm1.1Rze miceAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6
Jordans' anomaly and lamellar ichtyosis in Abhd5tm1.1Rze/Abhd5tm1.1Rze miceAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6
Increase in neutral lipid content in Abhd5tm1.1Rze/Abhd5tm1.1Rze and Pnpla2tm1Rze/Pnpla2tm1Rze liversAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6
Pnpla2tm1Rze/Pnpla2tm1Rzeinvolves: 129P2/OlaHsd
Disrupted epidermal permeability barrier and impaired keratinocyte differentiation in Abhd5tm1.1Rze/Abhd5tm1.1Rze mice but not Pnpla2tm1Rze/Pnpla2tm1Rze miceAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6
Pnpla2tm1Rze/Pnpla2tm1Rzeinvolves: 129P2/OlaHsd
Impaired hair growth and skin development of Abhd5tm1.1Rze/Abhd5tm1.1Rze skins grafted onto nude miceAbhd5tm1.1Rze/Abhd5tm1.1Rzeinvolves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory