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Phenotype Images associated with this Allele
Nomenclature
Symbol: Gt(ROSA)26Sortm1(ITK/SYK)Jrld
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jurgen Ruland
MGI ID: MGI:4460818
Synonyms: Rosa26loxSTOPlox-ITK-SYK
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Enlarged spleen in Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+ Tg(Cd4-cre)1Cwi/0 miceGt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Disruption of the splenic architecture with highly proliferative cells and solid organ infiltration of abnromal CD3+ T cells in Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+ Tg(Cd4-cre)1Cwi/0 miceGt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Enlarged spleen and solid organ infiltration with abnormally proliferating T cells in Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+ Cd19tm1(cre)Cgn/Cd19+ miceCd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+		involves: 129P2/OlaHsd
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory